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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Granisetron impurity B European Pharmacopoeia (EP) Reference Standard | 107007-95-4 |
Granisetron impurity B European Pharmacopoeia (EP) Reference Standard | Mol Wt: 298.38 | 107007-95-4 |
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Sigma Aldrich Fine Chemicals Biosciences Regorafenib United States200mg
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
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Medchemexpress LLC Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride | 2520105-60-4 | 98.6% | 498.45 g/mol | C23H31N5O3·2HCl | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cereblon (CRBN) ligand supplied as a hydrochloride salt for research use in PROTAC development and related synthetic chemistry. It provides an E3 ligase-binding moiety with a terminal piperidine handle to facilitate conjugation and linker attachment, and is supplied with supporting analytical documentation for research applications.
- Functionalized CRBN ligand suitable for PROTAC development.
- Hydrochloride salt provided as a solid for synthetic handling.
- High reported purity for research applications (≈98.6%).
- Small-scale research packaging ideal for medicinal chemistry (10 MG).
- Provides a terminal piperidine handle for conjugation and linker chemistry.
- Analytical documentation such as COA and SDS available.
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Sigma Aldrich Fine Chemicals Biosciences Betaine United States Pharmacopeia (USP) Reference Standard | 107-43-7 | MFCD00012123 | 1G
Betaine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 117.15 | 107-43-7 | MFCD00012123 | 1G
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Medchemexpress LLC Clarithromycin (Standard) | 81103-11-9 | 99.9% | 747.95 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Clarithromycin (Standard) is the analytical standard of Clarithromycin. This product is intended for research and analytical applications. It has a broad spectrum of antimicrobial activity and inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation. Clarithromycin also significantly inhibits the HERG potassium current and affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K.
- The compound is an analytical standard, which is the reference standard supplied assay.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Appearance: Solid.
- Color: White to off-white.
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Cayman Chemical GlyburIde-d3 5mg
An internal standard for the quantification of glyburide by GC- or LC-MS
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Selleck Chemical LLC Bimatoprost 50mg 155206-00-1
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Sigma Aldrich Fine Chemicals Biosciences Transplatin United States Pharmacopeia (USP) Reference Standard | 14913-33-8 | MFCD00011623 | 25MG
Transplatin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 300.05 | 14913-33-8 | MFCD00011623 | 25MG
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Sigma Aldrich Fine Chemicals Biosciences Methotrexate United States Pharmacopeia (USP) Reference Standard | 59-05-2 | MFCD00064370 | 500MG
Methotrexate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 454.44 | 59-05-2 | MFCD00064370 | 500MG
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Selleck Chemical LLC Camptothecin 10mM/1mL 7689-03-4 NSC-100880, CPT
Camptothecin (NSC-100880, CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 ?M in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Selleck Chemical LLC Fasudil (HA-1077) HCl 500mg 105628-07-7
Fasudil(HA-1077), a potent and selective inhibitor of Rho kinase, displays less potent inhibiton over PKA, PKG, PKC and MLCK with Ki of 1.6, 1.6, 3.3, and 36 ?M in cell-free assays, respectively. Fasudil is also a calcium channel blocker. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Sigma Aldrich Fine Chemicals Biosciences Naringin | 10236-47-2 | MFCD00148888 | 25g
Naringin | Purity: 95% | Mol Wt: 580.53 | 10236-47-2 | MFCD00148888 | 25g
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Sigma Aldrich Fine Chemicals Biosciences Oxiconazole nitrate United States Pharmacopeia (USP) Reference Standard | 64211-46-7 | 200MG
Oxiconazole nitrate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 492.14 | 64211-46-7 | 200MG
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Sigma Aldrich Fine Chemicals Biosciences Ibandronate Related Compound A United States Pharmacopeia (USP) Reference Standard | 625120-81-2 | 25MG
Ibandronate Related Compound A United States Pharmacopeia (USP) Reference Standard | Mol Wt: 209.71 | 625120-81-2 | 25MG
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Apexbio Technology LLC Flavopiridol hydrochloride 131740-09-5 100mg
Flavopiridol hydrochloride is a selective inhibitor of cyclin-dependent kinases (CDKs) specifically targeting CDK1 CDK2 CDK4 and CDK6 with reported IC50 values approximately 41 nM and CDK7 with an IC50 of about 300 nM Additionally it has been observed to inhibit EGFR and protein kinase A at micromolar concentrations By inhibiting CDK activity flavopiridol hydrochloride disrupts cell cycle progression inducing G1 phase arrest as demonstrated in breast cancer cell lines Furthermore its capacity to inhibit phosphorylation of Rb protein and suppress anti-apoptotic proteins such as Mcl-1 and XIAP facilitates apoptosis in lymphoma cell models Flavopiridol hydrochloride is utilized in preclinical studies of cell cycle regulation apoptosis signaling and cancer research including experiments using xenograft tumor models in mice
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